Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.37 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638021 | 0.98 | TDP1 (0.43) | TDP1PSMB5FASNCPB1CPB2 | |
| SCHEMBL9637913 | 0.97 | TDP1 (0.41) | TDP1PSMB5FASNCPB1CPB2 | |
| SCHEMBL10694865 | 0.97 | TDP1 (0.41) | TDP1PSMB5FASNCPB1CPB2 | |
| SCHEMBL9636912 | 0.91 | TDP1 (0.43) | TDP1PSMB5FASNCPB1CPB2 | |
| SCHEMBL9638053 | 0.91 | REN (0.44) | P2RY6P2RY14NT5E | |
| SCHEMBL9637216 | 0.90 | P2RY6 (0.44) | P2RY6P2RY14NT5E | |
| SCHEMBL9637218 | 0.90 | P2RY6 (0.44) | P2RY6P2RY14NT5E | |
| SCHEMBL9636996 | 0.89 | TYMS (0.44) | P2RY6P2RY14NT5E | |
| SCHEMBL9637000 | 0.89 | TYMS (0.44) | P2RY6P2RY14NT5E | |
| SCHEMBL9637176 | 0.87 | CYP3A4 (0.47) | P2RY6P2RY14NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268678-B1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-29 | — | — | EP | disclosed |
| EP-0268678-A1 | NOVEL 5-FLUOROURIDINE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-06-01 | — | — | EP | disclosed |