Sugi Predict

Sugi Predict / Compounds / SCHEMBL9638438

SCHEMBL9638438

SCHEMBL9638438

COC(=O)OC(=O)OC(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DGAT1 O75907 1/20 0.46
▸ HDAC6 Q9UBN7 2/20 0.37
▸ HDAC1 Q13547 1/20 0.37
▸ HDAC2 Q92769 1/20 0.37
▸ ELANE P08246 1/20 0.36
▸ CA12 O43570 2/20 0.36
▸ CA14 Q9ULX7 2/20 0.36
▸ CA2 P00918 2/20 0.35
▸ CA1 P00915 1/20 0.35
▸ CA7 P43166 1/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ USP2 O75604 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ APLNR P35414 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ CTSK P43235 3/20 0.32
▸ CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5452 0.89 DGAT1 (0.42) DGAT1HDAC6HDAC1HDAC2ELANE
SCHEMBL8375577 0.89 DGAT1 (0.42) DGAT1HDAC6HDAC1HDAC2ELANE
SCHEMBL31469549 0.86 DGAT1 (0.40) DGAT1HDAC6HDAC1HDAC2ELANE
SCHEMBL29482425 0.86 DGAT1 (0.40) DGAT1HDAC6HDAC1HDAC2ELANE
SCHEMBL1145251 0.86 DGAT1 (0.40) DGAT1HDAC6HDAC1HDAC2ELANE
SCHEMBL29808062 0.86 DGAT1 (0.40) DGAT1HDAC6HDAC1HDAC2ELANE
SCHEMBL187785 0.86 — —
Hydrochloric Acid SCHEMBL28367906 0.86 DGAT1 (0.40) DGAT1HDAC6HDAC1HDAC2ELANE
SCHEMBL29740062 0.86 DGAT1 (0.40) DGAT1HDAC6HDAC1HDAC2ELANE
SCHEMBL28072361 0.86 DGAT1 (0.40) DGAT1HDAC6HDAC1HDAC2ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109160964-B High molecular weight polypropylene alcohol polymer and preparation method and application thereof 万华化学（宁波）有限公司 2021-04-20 — — CN claimed
JP-3068636-A — — None — — JP disclosed
US-20240383876-A1 TLR7/8 ANTAGONISTS AND USES THEREOF MERCK PATENT GMBH (DE) 2024-11-21 — — US disclosed
US-20230357467-A1 FLUORINE-CONTAINING COPOLYMER PRODUCTION METHOD AND FLUORINE-CONTAINING COPOLYMER AGC Inc. (JP) 2023-11-09 — — US disclosed
EP-4198031-A1 TLR7/8 ANTAGONISTS AND USES THEREOF Merck Patent GmbH (DE) 2023-06-21 — — EP disclosed
EP-3497094-B1 TLR7/8 ANTAGONISTS AND USES THEREOF MERCK PATENT GMBH (DE) 2023-02-15 — — EP disclosed
US-11512069-B2 TLR7/8 antagonists and uses thereof MERCK PATENT GMBH (DE) 2022-11-29 — — US disclosed
CN-110373026-B Polyimide resin composition, method for producing the same, and film 无锡创彩光学材料有限公司 2021-06-29 — — CN disclosed
CN-109160964-B High molecular weight polypropylene alcohol polymer and preparation method and application thereof 万华化学（宁波）有限公司 2021-04-20 — — CN disclosed
US-10947214-B2 TLR7/8 antagonists and uses thereof MERCK PATENT GMBH (DE) 2021-03-16 — — US disclosed
US-20180037570-A1 TLR7/8 ANTAGONISTS AND USES THEREOF MERCK PATENT GMBH (DE) 2018-02-08 — — US disclosed
US-9221851-B2 Mixture containing a monophosphite ligand and the use thereof for catalysis of a hydroformylation reaction EVONIK INDUSTRIES AG (DE) 2015-12-29 — — US disclosed
US-8859194-B2 Polymer compound, and resist-protecting film composition including same for a liquid immersion exposure process DONGJIN SEMICHEM CO., LTD. (KR) 2014-10-14 — — US disclosed
US-20130252170-A1 Polymer Compound, And Resist-Protecting Film Composition Including Same For A Liquid Immersion Exposure Process DONGJIN SEMICHEM CO., LTD. (KR) 2013-09-26 — — US disclosed
US-5140052-A Using a tertiary amine as a dicarbonate decomposition catalyst along with water as a promoter in foam-producing systems at environmental temperatures AKZO N.V. (NL) 1992-08-18 — — US disclosed
US-5086083-A Tertiary amine decomposition catalysts; nontoxic; environmentally acceptable AKZO NV (NL) 1992-02-04 — — US disclosed
US-5030664-A Combining with a tertiary amine decomposition catalyst to produce carbon dioxide in polyurethanes AKZO N.V. (NL) 1991-07-09 — — US disclosed
JP-H0368636-A DIALKYL DICARBONATE AS FOAMING AGENT FOR POLYMER AKZO NV 1991-03-25 — — JP disclosed
US-4983320-A Tertiary amine decomposition catalysts; polyurethane foams AKZO N.V. (NL) 1991-01-08 — — US disclosed
EP-0400709-A2 Dialkyl dicarbonates as blowing agents for polymers Akzo Nobel N.V. (NL) 1990-12-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180037570-A1 TLR7/8 ANTAGONISTS AND USES THEREOF TLR7, TLR8, TLR9 DGAT1 1402/4885HDAC6 860/4885HDAC1 1501/4885
US-11512069-B2 TLR7/8 antagonists and uses thereof TLR7, TLR8, TLR9 DGAT1 1699/4885HDAC6 615/4885HDAC1 958/4885
US-10947214-B2 TLR7/8 antagonists and uses thereof TLR7, TLR8, TLR9 DGAT1 1402/4885HDAC6 860/4885HDAC1 1501/4885
US-20240383876-A1 TLR7/8 ANTAGONISTS AND USES THEREOF TLR7, TLR8, TLR9 DGAT1 1649/4885HDAC6 888/4885HDAC1 1108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.