Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637237 | 0.87 | FGFR1 (0.58) | FGFR1HPGDALDH1A1LMNAHTT | |
| SCHEMBL9725324 | 0.84 | FGFR1 (0.58) | FGFR1HPGDALDH1A1LMNAHTT | |
| SCHEMBL16148147 | 0.80 | HPGD (0.53) | FGFR1HPGDALDH1A1LMNAHTT | |
| SCHEMBL29526516 | 0.79 | FGFR1 (0.71) | FGFR1HPGDHTTTHRB | |
| SCHEMBL1354830 | 0.79 | FGFR1 (0.71) | FGFR1HPGDHTTTHRB | |
| SCHEMBL1816262 | 0.79 | FGFR1 (0.70) | FGFR1HTT | |
| SCHEMBL15990423 | 0.77 | POLB (0.56) | FGFR1HPGDALDH1A1LMNAHTT | |
| SCHEMBL12822201 | 0.77 | FGFR1 (0.67) | FGFR1HPGDALDH1A1LMNATSHR | |
| SCHEMBL2810948 | 0.76 | HTT (0.54) | FGFR1HPGDALDH1A1LMNAHTT | |
| SCHEMBL9725330 | 0.76 | HTT (0.50) | FGFR1HPGDALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081256-A | Para ordered aromatic diacids containing benzimidazole groups | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-01-14 | — | — | US | claimed |
| US-5140092-A | Rigid-rod benzimidazole pendant benzobisazo polymer | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-08-18 | — | — | US | disclosed |
| US-5081256-A | Para ordered aromatic diacids containing benzimidazole groups | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-01-14 | — | — | US | disclosed |
| US-5081256-A | Para ordered aromatic diacids containing benzimidazole groups | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1992-01-14 | — | — | US | disclosed |