Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16148147 | 0.82 | HPGD (0.53) | FGFR1ALDH1A1HPGDLMNARXRA | |
| Hydrochloric Acid SCHEMBL7986276 | 0.79 | FGFR1 (0.97) | FGFR1ALDH1A1HPGDSRC | |
| SCHEMBL12822182 | 0.79 | FGFR1 (0.80) | FGFR1HPGDTHRBSRC | |
| SCHEMBL27995809 | 0.78 | HTT (0.58) | FGFR1ALDH1A1HPGDHCAR1KDM4E | |
| SCHEMBL9638534 | 0.77 | FGFR1 (0.59) | FGFR1ALDH1A1HPGDLMNARXRA | |
| SCHEMBL12822066 | 0.77 | FGFR1 (0.47) | FGFR1ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL12817507 | 0.76 | FGFR1 (0.84) | FGFR1HPGDTHRBSRC | |
| SCHEMBL2076390 | 0.76 | FGFR1 (0.70) | FGFR1ALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL3734995 | 0.75 | CXCR3 (0.52) | FGFR1LMNASMN1; SMN2TBXA2RF2 | |
| SCHEMBL9637237 | 0.73 | FGFR1 (0.58) | FGFR1ALDH1A1HPGDLMNARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012131501-A1 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AS COT KINASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2012-10-04 | — | — | WO | claimed |
| WO-2012131501-A1 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AS COT KINASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2012-10-04 | — | — | WO | disclosed |