SCHEMBL9638650

SCHEMBL9638650

Cc1ccc(N2C(=O)c3ccc4c5ccc6c7c(ccc(c8ccc(c3c48)C2=O)c75)C(=O)N(c2ccc(C)cc2)C6=O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
RAB9A P51151 2/20 0.57
NPC1 O15118 1/20 0.57
TSHR P16473 1/20 0.57
CASP1 P29466 1/20 0.57
CASP7 P55210 1/20 0.57
HSD17B10 Q99714 1/20 0.57
POLB P06746 3/20 0.56
APAF1 O14727 1/20 0.56
KDM4E B2RXH2 2/20 0.56
CA9 Q16790 4/20 0.53
CA12 O43570 3/20 0.51
CA1 P00915 3/20 0.51
CA2 P00918 2/20 0.50
F2 P00734 1/20 0.50
ELANE P08246 1/20 0.50
CTSG P08311 1/20 0.50
CMA1 P23946 1/20 0.50
CTRC Q99895 1/20 0.50
ADORA2A P29274 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11990862 0.92 ALDH1A1 (0.70) ALDH1A1RAB9ANPC1TSHRCASP1
SCHEMBL15672159 0.89 ESR1 (0.57) ALDH1A1RAB9ANPC1TSHRCASP1
SCHEMBL14409657 0.85 CYP2D6 (0.52) ALDH1A1RAB9ANPC1TSHRCASP1
SCHEMBL13533868 0.85 ALDH1A1 (0.62) ALDH1A1RAB9ANPC1TSHRCASP1
SCHEMBL29354879 0.84 MEN1 (0.49) ALDH1A1RAB9ANPC1TSHRCASP1
SCHEMBL1078941 0.84 MEN1 (0.49) ALDH1A1RAB9ANPC1TSHRCASP1
SCHEMBL18470167 0.84 POLB (0.82) ALDH1A1RAB9ANPC1TSHRCASP1
SCHEMBL18470162 0.82 ALDH1A1 (0.58) ALDH1A1RAB9ANPC1TSHRCASP1
SCHEMBL24221089 0.81 POLB (0.56) ALDH1A1RAB9ANPC1POLBAPAF1
SCHEMBL3401969 0.81 KMT2A (0.61) ALDH1A1RAB9ANPC1POLBAPAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100330496-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING-REPRODUCTION METHOD, AND SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING MATERIAL FOR USE THEREIN FUJIFILM CORPORATION (JP) 2010-12-30 US disclosed
US-20100330496-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING-REPRODUCTION METHOD, AND SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING MATERIAL FOR USE THEREIN FUJIFILM CORPORATION (JP) 2010-12-30 US disclosed
US-7259229-B2 Electroactive fluorene polymers having perfluoralkyl groups, process for preparing such polymers and devices made with such polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2007-08-21 US disclosed
US-7214763-B2 Electroactive fluorene copolymers and devices made with such polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-05-08 US disclosed
US-7183366-B2 Aromatic copolymers from dihalofluorene compounds and another dihalo- or diborono- aromatic monomers; organic electroluminescent polymers for use in light-emitting diodes E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-02-27 US disclosed
EP-0281381-B1 ELECTROLUMINESCENT DEVICE WITH MODIFIED THIN FILM LUMINESCENT ZONE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-07-15 EP disclosed
EP-0349265-A2 Electroluminescent devices EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1990-01-03 EP disclosed
US-4769292-A Electroluminescent device with modified thin film luminescent zone EASTMAN KODAK COMPANY (US) 1988-09-06 US disclosed