Sulfuric Acid

Sulfuric Acid

SCHEMBL9638833

CCN(CC)c1ccc(NCCO)c(C)c1.O=S(=O)(O)O

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RPS6KA2 Q15349 1/20 0.50
POLB P06746 4/20 0.46
GRK2 P25098 1/20 0.46
DNMT1 P26358 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
MAPT P10636 10/20 0.46
GAA P10253 4/20 0.46
GFER P55789 6/20 0.46
HTT P42858 4/20 0.46
LMNA P02545 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
CYP2C19 P33261 2/20 0.46
CYP1A2 P05177 1/20 0.46
MAPK1 P28482 5/20 0.45
ALDH1A1 P00352 5/20 0.45
ALOX15 P16050 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HSD17B10 Q99714 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11330687 0.83 RPS6KA2 (0.52) RPS6KA2POLBGRK2DNMT1CTDSP1
Sulfuric Acid SCHEMBL6552337 0.82 MAPT (0.50) RPS6KA2POLBGRK2DNMT1CTDSP1
SCHEMBL5692626 0.81 RPS6KA2 (0.50) RPS6KA2POLBGRK2DNMT1CTDSP1
SCHEMBL9555083 0.80 MAPT (0.56) RPS6KA2POLBGRK2DNMT1CTDSP1
SCHEMBL8594962 0.78 RPS6KA2 (0.52) RPS6KA2POLBGRK2DNMT1CTDSP1
Sulfuric Acid SCHEMBL28617571 0.77 ALDH1A1 (0.49) POLBMAPTGAAGFERHTT
Sulfuric Acid SCHEMBL9334547 0.77 MAPT (0.38) POLBMAPTHTTLMNASMN1; SMN2
SCHEMBL3813035 0.77 MAPT (0.48) RPS6KA2POLBGRK2DNMT1CTDSP1
Sulfuric Acid SCHEMBL4626210 0.77 MAPT (0.43) POLBMAPTGAACYP2C19CYP1A2
Sulfuric Acid SCHEMBL11060632 0.75 MAPT (0.42) POLBMAPTGAACYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227358-B1 HOUSING PACK FOR PHOTOGRAPHIC PROCESSING SOLUTION KONICA CORPORATION (JP) 1992-08-12 EP disclosed
US-4791013-A STORAGE AND WASTE COMPARTMENTS; OXYGEN BARRIER MEMBRANE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-12-13 US disclosed
EP-0227358-A2 Housing pack for photographic processing solution KONICA CORPORATION (JP) 1987-07-01 EP disclosed