SCHEMBL9639006

SCHEMBL9639006

COc1ccc(C(=O)c2ccc(O)c(O)c2O)c(O)c1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.65
KDM4E B2RXH2 6/20 0.65
HSD17B10 Q99714 5/20 0.65
ALOX15 P16050 5/20 0.65
ALDH1A1 P00352 4/20 0.65
HPGD P15428 4/20 0.65
MAPK1 P28482 3/20 0.65
LMNA P02545 3/20 0.65
RECQL P46063 3/20 0.65
CYP3A4 P08684 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
HDAC1 Q13547 1/20 0.50
ALOX12 P18054 2/20 0.48
TP53 P04637 1/20 0.48
SELL P14151 1/20 0.48
SELP P16109 1/20 0.48
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
RAB9A P51151 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11776410 0.89 MAPT (0.66) MAPTKDM4EHSD17B10ALOX15ALDH1A1
SCHEMBL3327695 0.84 MAPT (0.55) MAPTKDM4EHSD17B10ALOX15ALDH1A1
SCHEMBL21752003 0.84 MAPT (0.69) MAPTKDM4EHSD17B10ALOX15ALDH1A1
SCHEMBL9742294 0.84 KDM4E (0.65) MAPTKDM4EHSD17B10ALOX15ALDH1A1
SCHEMBL28008546 0.82 MAPT (0.71) MAPTKDM4EHSD17B10ALOX15ALDH1A1
SCHEMBL1063407 0.82 SELL (0.68) MAPTKDM4EHSD17B10ALOX15ALDH1A1
SCHEMBL9639578 0.81 MAPT (0.69) MAPTKDM4EHSD17B10ALOX15ALDH1A1
SCHEMBL9639024 0.81 KDM4E (0.63) MAPTKDM4EHSD17B10ALOX15ALDH1A1
SCHEMBL19003423 0.80 HDAC1 (0.72) MAPTKDM4EHSD17B10ALOX15ALDH1A1
SCHEMBL29670589 0.80 SLC22A6 (0.72) MAPTKDM4EHSD17B10ALOX15ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0227487-B1 POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-07-15 EP disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed