Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10983450 | 0.83 | ALDH1A1 (0.42) | EPHX1ALDH1A1TP53KDM4EGMNN | |
| SCHEMBL2398883 | 0.81 | ALDH1A1 (0.55) | EPHX1ALDH1A1TP53KDM4EGMNN | |
| SCHEMBL3149068 | 0.78 | EPHX1 (0.52) | EPHX1ALDH1A1TP53KDM4EGMNN | |
| SCHEMBL2398177 | 0.78 | ALDH1A1 (0.52) | EPHX1ALDH1A1TP53 | |
| SCHEMBL1698454 | 0.77 | TP53 (0.56) | EPHX1ALDH1A1TP53KDM4EGMNN | |
| SCHEMBL15774470 | 0.77 | EPHX1 (0.50) | EPHX1ALDH1A1TP53KDM4EGMNN | |
| Hydrochloric Acid SCHEMBL30875135 | 0.77 | EPHX1 (0.50) | EPHX1ALDH1A1TP53KDM4EGMNN | |
| SCHEMBL29051498 | 0.76 | EPHX1 (0.48) | EPHX1ALDH1A1TP53KDM4EGMNN | |
| SCHEMBL13999779 | 0.75 | EPHX1 (0.48) | EPHX1ALDH1A1TP53 | |
| SCHEMBL931422 | 0.75 | EPHX1 (0.48) | EPHX1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314450-B1 | PREPARATION OF HALO SUBSTITUTED ISOTHIAZOLONES | ROHM AND HAAS COMPANY (US) | 1992-07-29 | — | — | EP | disclosed |
| US-4861896-A | Preparation of halo substituted isothiazolones | ROHM AND HAAS COMPANY (US) | 1989-08-29 | — | — | US | disclosed |
| EP-0314450-A1 | Preparation of halo substituted isothiazolones | ROHM AND HAAS COMPANY (US) | 1989-05-03 | — | — | EP | disclosed |