Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398177 | 0.98 | ALDH1A1 (0.52) | ALDH1A1EPHX1TP53SLC22A6 | |
| SCHEMBL27447571 | 0.89 | — | — | |
| SCHEMBL10983450 | 0.84 | ALDH1A1 (0.42) | ALDH1A1EPHX1TP53LMNAMAPT | |
| SCHEMBL7581255 | 0.82 | ALDH1A1 (0.59) | ALDH1A1EPHX1TP53LMNAMAPT | |
| SCHEMBL9639145 | 0.81 | EPHX1 (0.48) | ALDH1A1EPHX1TP53LMNAMAPT | |
| SCHEMBL4728813 | 0.79 | ALDH1A1 (0.55) | ALDH1A1EPHX1TP53LMNAMAPT | |
| SCHEMBL28480892 | 0.77 | ALDH1A1 (0.77) | ALDH1A1EPHX1TP53LMNAMAPT | |
| SCHEMBL11469650 | 0.77 | ALDH1A1 (0.41) | ALDH1A1EPHX1LMNABLM | |
| SCHEMBL5195787 | 0.76 | ALDH1A1 (0.37) | ALDH1A1EPHX1TP53LMNASMN1; SMN2 | |
| SCHEMBL3864316 | 0.76 | ALDH1A1 (0.57) | ALDH1A1EPHX1TP53LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130274470-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-10-17 | — | — | US | disclosed |
| US-20110224431-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274470-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | HDHD5, DCX, CLK2 | ALDH1A1 4532/4885EPHX1 3839/4885TP53 1108/4885 |
| US-20110224431-A1 | Triazolium Carbene Catalysts and Stereoselective Bond Forming Reactions Thereof | HDHD5, DCX, CLK2 | ALDH1A1 4532/4885EPHX1 3839/4885TP53 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.