SCHEMBL9639293

SCHEMBL9639293

CCc1ccc(O)c(-n2nc3ccc(Cl)cc3n2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.46
RAB9A P51151 4/20 0.46
LMNA P02545 2/20 0.46
TRPA1 O75762 1/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
RORC P51449 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38
MAPT P10636 6/20 0.38
TP53 P04637 2/20 0.38
THRB P10828 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
IDO1 P14902 2/20 0.35
KCNMA1 Q12791 1/20 0.34
AKR1B1 P15121 1/20 0.34
SLC22A1 O15245 1/20 0.33
USP2 O75604 1/20 0.33
HSP90AA1 P07900 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9638776 0.89 NPC1 (0.43) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL9638427 0.89 TRPA1 (0.41) NPC1RAB9ALMNATRPA1MEN1
SCHEMBL13699403 0.87 NPC1 (0.43) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL2589692 0.87 NPC1 (0.42) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL27322664 0.86 MEN1 (0.42) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL9240944 0.86 IGF1R (0.43) NPC1RAB9ALMNATP53KDM4E
SCHEMBL11418479 0.85 NPC1 (0.51) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL7566832 0.85 MAPT (0.42) NPC1RAB9ALMNAMEN1KMT2A
SCHEMBL31252564 0.85 KAT8 (0.43) NPC1RAB9ALMNATP53KDM4E
SCHEMBL13700392 0.84 NPC1 (0.47) NPC1RAB9ALMNATRPA1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0208211-B1 WATER-INSOLUBLE DISPERSE DYE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-02 EP disclosed
EP-0164223-B1 METHOD FOR DYEING POLYESTER FIBER MATERIALS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-12-05 EP disclosed
US-4690686-A HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-09-01 US disclosed
EP-0208211-A2 Water-insoluble disperse dye composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-01-14 EP disclosed
US-4626257-A Method for dyeing polyester fiber materials: disperse dye combinations with compensated color fading SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-12-02 US disclosed
EP-0164223-A2 Method for dyeing polyester fiber materials SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-12-11 EP disclosed