SCHEMBL7566832

SCHEMBL7566832

OCCc1ccc(O)c(-n2nc3ccc(Cl)cc3n2)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.42
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 3/20 0.42
ALOX5 P09917 1/20 0.42
GAA P10253 1/20 0.42
BACE1 P56817 1/20 0.42
ALOX15 P16050 3/20 0.41
HPGD P15428 3/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
LMNA P02545 3/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
AKR1B1 P15121 1/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
IGF1R P08069 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8649490 0.92 ALOX15 (0.42) MAPTKDM4EALDH1A1ALOX5GAA
SCHEMBL28755473 0.91 ALOX15 (0.44) KDM4EALDH1A1BACE1ALOX15HPGD
SCHEMBL30240998 0.91 ALOX15 (0.44) KDM4EALDH1A1BACE1ALOX15HPGD
SCHEMBL13699403 0.89 NPC1 (0.43) MAPTKDM4EALOX15HPGDHSD17B10
SCHEMBL9638776 0.88 NPC1 (0.43) MAPTKDM4EALOX5ALOX15LMNA
SCHEMBL13699348 0.87 KDM4E (0.46) MAPTKDM4EALDH1A1ALOX5GAA
SCHEMBL2589692 0.86 NPC1 (0.42) MAPTALOX15HPGDPOLBMAPK1
SCHEMBL9639293 0.85 NPC1 (0.46) MAPTKDM4EALOX15HPGDLMNA
SCHEMBL27322664 0.85 MEN1 (0.42) MAPTKDM4EALDH1A1ALOX15HPGD
SCHEMBL9240944 0.85 IGF1R (0.43) KDM4EALDH1A1ALOX15HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0131468-B1 ULTRAVIOLET ABSORBING POLYMERS COMPRISING 2-HYDROXY-5-ACRYLYLOXALKYLPHENYL-2H-BENZOTRIAZOLES IOLAB CORPORATION (US) 1990-01-17 EP claimed
US-4611061-A 2'-hydroxy-5'-(hydroxyalkyl)phenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1986-09-09 US claimed
EP-0131468-A2 Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxalkylphenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1985-01-16 EP claimed
US-8324399-B2 Heat resistance improver and reversible thermosensitive recording medium RICOH COMPANY, LTD. (JP) 2012-12-04 US disclosed
US-20090239747-A1 HEAT RESISTANCE IMPROVER AND REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM RICOH COMPANY, LTD. (JP) 2009-09-24 US disclosed
CN-100528989-C Anion electroplating paint and finished articles KANSAI PAINT CO LTD (JP) 2009-08-19 CN disclosed
CN-1673295-A Anion electroplating paint and finished articles KANSAI PAINT CO LTD (JP) 2005-09-28 CN disclosed
EP-0855393-B1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KK (JP) 2002-08-14 EP disclosed
US-5922882-A ULTRAVIOLET RADIATION ABSORBER; COPOLYMERIZATION COMPONENT OF BISBENZOTRIAZOLE COMPRISING A COPOLYCARBONATE, A COPOLYESTER, A COPOLYURETHANE AND A COPOLYURETHANEURA OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1999-07-13 US disclosed
US-5814438-A Benzotriazole-based novel UV absorbers and photographic elements containing them EASTMAN KODAK COMPANY (US) 1998-09-29 US disclosed
EP-0855393-A1 BISBENZOTRIAZOLYLPHENOLS OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1998-07-29 EP disclosed
US-5675015-A Process for the preparation of benzotriazole derivatives EASTMAN KODAK COMPANY (US) 1997-10-07 US disclosed
EP-0131468-B1 ULTRAVIOLET ABSORBING POLYMERS COMPRISING 2-HYDROXY-5-ACRYLYLOXALKYLPHENYL-2H-BENZOTRIAZOLES IOLAB CORPORATION (US) 1990-01-17 EP disclosed
US-4611061-A 2'-hydroxy-5'-(hydroxyalkyl)phenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1986-09-09 US disclosed
EP-0131468-A2 Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxalkylphenyl-2H-benzotriazoles IOLAB CORPORATION (US) 1985-01-16 EP disclosed