Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 5/20 | 0.71 |
| ▸ | CASP5 | P51878 | 5/20 | 0.71 |
| ▸ | CASP4 | P49662 | 4/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.53 |
| ▸ | GBA1 | P04062 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL9639430 | 0.87 | CASP1 (0.78) | CASP1CASP5CASP4SMN1; SMN2USP2 | |
| SCHEMBL9640542 | 0.87 | CASP1 (0.64) | CASP1CASP5CASP4SMN1; SMN2USP2 | |
| SCHEMBL6505711 | 0.84 | CASP1 (1.00) | CASP1CASP5CASP4SMN1; SMN2USP2 | |
| SCHEMBL9492704 | 0.84 | CASP1 (1.00) | CASP1CASP5CASP4SMN1; SMN2USP2 | |
| SCHEMBL7773886 | 0.81 | CASP1 (0.93) | CASP1CASP5CASP4SMN1; SMN2USP2 | |
| SCHEMBL9640154 | 0.81 | CASP1 (0.59) | CASP1CASP5CASP4SMN1; SMN2USP2 | |
| 1-Hexanol SCHEMBL9688181 | 0.80 | CASP1 (0.66) | CASP1CASP5CASP4SMN1; SMN2USP2 | |
| 1-Hexanol SCHEMBL9690248 | 0.79 | CASP1 (0.64) | CASP1CASP5CASP4SMN1; SMN2USP2 | |
| SCHEMBL8891695 | 0.78 | CASP1 (0.78) | CASP1CASP5CASP4SMN1; SMN2USP2 | |
| SCHEMBL8900887 | 0.78 | CASP1 (0.78) | CASP1CASP5CASP4SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496746-A1 | PHARMACEUTICALLY ACTIVE AMINO-SUBSTITUTED HETEROARYL AMINES | THE UPJOHN COMPANY (US) | 1992-08-05 | — | — | EP | claimed |