SCHEMBL963960

SCHEMBL963960

CCOCCOCC(O)OC

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 1/20 0.39
TSHR P16473 2/20 0.38
THRB P10828 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
USP2 O75604 1/20 0.32
HTT P42858 1/20 0.31
LPAR6 P43657 3/20 0.31
LPAR1 Q92633 3/20 0.31
LPAR4 Q99677 3/20 0.31
LPAR5 Q9H1C0 3/20 0.31
LPAR2 Q9HBW0 3/20 0.31
LPAR3 Q9UBY5 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15765884 0.90 HSD17B10 (0.40) HSD17B10TSHRTDP1USP2HTT
SCHEMBL12371277 0.87
Propylene Glycol SCHEMBL11467409 0.80 ALDH1A1 (0.42) ALDH1A1HSD17B10TSHRTHRBTDP1
Propylene Glycol SCHEMBL11468356 0.80 ALDH1A1 (0.42) ALDH1A1HSD17B10TSHRTHRBTDP1
SCHEMBL9720673 0.79 MEN1 (0.50) ALDH1A1HSD17B10TSHRTHRBUSP2
SCHEMBL829630 0.79 MEN1 (0.50) ALDH1A1HSD17B10TSHRTHRBUSP2
SCHEMBL829172 0.79 MEN1 (0.50) ALDH1A1HSD17B10TSHRTHRBUSP2
SCHEMBL829553 0.79 MEN1 (0.50) ALDH1A1HSD17B10TSHRTHRBUSP2
SCHEMBL98075 0.79 MEN1 (0.50) ALDH1A1HSD17B10TSHRTHRBUSP2
SCHEMBL679835 0.79 MEN1 (0.50) ALDH1A1HSD17B10TSHRTHRBUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2274383-B1 PROCESS FOR THE SURFACE MODIFICATION OF PARTICLES 3M INNOVATIVE PROPERTIES CO (US) 2018-04-25 EP claimed
US-8394977-B2 Process for the surface modification of particles 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-03-12 US claimed
US-20110021797-A1 PROCESS FOR THE SURFACE MODIFICATION OF PARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2011-01-27 US claimed
EP-2274383-A2 PROCESS FOR THE SURFACE MODIFICATION OF PARTICLES 3M Innovative Properties Company (US) 2011-01-19 EP claimed
WO-2009120846-A2 PROCESS FOR THE SURFACE MODIFICATION OF PARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-10-01 WO claimed