Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.64 |
| ▸ | EBP | Q15125 | 2/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9354199 | 0.95 | SIGMAR1 (0.64) | SIGMAR1EBPABCB1CYP3A4CYP3A5 | |
| SCHEMBL9625375 | 0.95 | SIGMAR1 (0.64) | SIGMAR1EBPABCB1CYP3A4CYP3A5 | |
| Hydrochloric Acid SCHEMBL9357344 | 0.94 | SIGMAR1 (0.62) | SIGMAR1EBPABCB1CYP3A4CYP3A5 | |
| SCHEMBL10770803 | 0.92 | SIGMAR1 (0.55) | SIGMAR1EBPABCB1CYP3A4CYP3A5 | |
| SCHEMBL9490838 | 0.92 | SIGMAR1 (0.55) | SIGMAR1EBPABCB1CYP3A4CYP3A5 | |
| SCHEMBL9493520 | 0.89 | SIGMAR1 (0.52) | SIGMAR1EBPABCB1CYP3A4CYP3A5 | |
| SCHEMBL9491747 | 0.87 | ABCB1 (0.57) | SIGMAR1EBPABCB1CYP3A4CYP3A5 | |
| SCHEMBL9490484 | 0.87 | ABCB1 (0.57) | SIGMAR1EBPABCB1CYP3A4CYP3A5 | |
| SCHEMBL9492266 | 0.86 | ABCB1 (0.56) | SIGMAR1EBPABCB1CYP3A4CYP3A5 | |
| SCHEMBL9492262 | 0.86 | ABCB1 (0.56) | SIGMAR1EBPABCB1CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270782-B1 | THERAPEUTIC AGENTS FOR THE PROPHYLAXIS OF TUMOUR METASTASIS | BASF Aktiengesellschaft (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0268100-B1 | ACTIVE SUBSTANCES FOR USE IN THE TREATMENT OF TUMOURS | BASF Aktiengesellschaft (DE) | 1991-06-12 | — | — | EP | disclosed |
| EP-0270782-A2 | Therapeutic agents for the prophylaxis of tumour metastasis | BASF Aktiengesellschaft (DE) | 1988-06-15 | — | — | EP | disclosed |
| EP-0268100-A1 | Active substances for use in the treatment of tumours | BASF Aktiengesellschaft (DE) | 1988-05-25 | — | — | EP | disclosed |