Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85152 | 0.85 | MAPT (0.47) | S100BMAPTATMNPSR1LMNA | |
| SCHEMBL12305568 | 0.78 | MAPT (0.46) | MAPTATMNPSR1LMNACYP2A6 | |
| SCHEMBL11411073 | 0.76 | CA2 (0.67) | S100BMAPTNPSR1LMNATDP1 | |
| SCHEMBL2454124 | 0.76 | CA2 (0.67) | S100BMAPTNPSR1LMNATDP1 | |
| SCHEMBL20186937 | 0.76 | CA2 (0.67) | S100BMAPTNPSR1LMNATDP1 | |
| SCHEMBL11411078 | 0.76 | CA2 (0.67) | S100BMAPTNPSR1LMNATDP1 | |
| SCHEMBL2454125 | 0.76 | CA2 (0.67) | S100BMAPTNPSR1LMNATDP1 | |
| SCHEMBL28766487 | 0.75 | ALDH1A1 (0.51) | MAPTATMNPSR1LMNACYP2C19 | |
| SCHEMBL23644537 | 0.74 | MAPT (0.43) | MAPTATMNPSR1LMNACYP2A6 | |
| SCHEMBL28380320 | 0.71 | MAPT (0.41) | MAPTATMNPSR1CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280373-B1 | PROCESS FOR THE DIMERIZATION OF OLEFINS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-08-12 | — | — | EP | disclosed |
| US-4859646-A | Process for the dimerization of olefins | SHELL OIL COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
| US-4806647-A | PALLADIUM(II) COMPOUND, CHELATE LIGAND, PROTONIC ACID AND SALT | SHELL OIL COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0170311-B1 | PROCESS FOR THE DIMERIZATION OF OLEFINS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-02-01 | — | — | EP | disclosed |
| US-4692548-A | DIMERIZATION OF ETHYLENICALLY UNSATURATED COMPOUNDS | SHELL OIL COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| US-4634793-A | PALLADIUM CATALYST SYSTEM | SHELL OIL COMPANY (US) | 1987-01-06 | — | — | US | disclosed |
| EP-0206367-A2 | Process for the dimerization of ethylenically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-12-30 | — | — | EP | disclosed |