Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 5/20 | 0.36 |
| ▸ | CDK1 | P06493 | 4/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 3/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639625 | 0.77 | ALDH1A1 (0.46) | GAAMAPTTP53ALOX15HSD17B10 | |
| SCHEMBL134909 | 0.71 | PDPK1 (0.49) | DPP4ENPP1CDK2CDK1CCNB1 | |
| SCHEMBL4845432 | 0.71 | CDK2 (0.53) | DPP4HSD17B10ENPP1CDK2CDK1 | |
| SCHEMBL28141587 | 0.69 | DPP4 (0.42) | DPP4HSD17B10CDK2PNPPDPK1 | |
| SCHEMBL28758673 | 0.68 | MGMT (0.53) | DPP4HSD17B10ENPP1CDK2CDK1 | |
| SCHEMBL27946157 | 0.68 | MAPT (0.57) | GAAMAPTHDAC1TP53ALOX15 | |
| SCHEMBL9952179 | 0.66 | GAA (0.53) | GAAMAPTTP53ALOX15HSD17B10 | |
| SCHEMBL112507 | 0.65 | MAPT (0.74) | GAAMAPTTP53ALOX15HSD17B10 | |
| SCHEMBL30790667 | 0.65 | MAPT (0.74) | GAAMAPTTP53ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL11745887 | 0.63 | MAPT (0.71) | GAAMAPTTP53ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153180-A | Used for treating aids | BURROUGHS WELLCOME CO. | 1992-10-06 | — | — | US | disclosed |