Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639884 | 0.85 | ESR1 (0.34) | CYP3A4ALDH1A1MAPTSMN1; SMN2CYP2C19 | |
| SCHEMBL9639422 | 0.84 | CYP3A4 (0.33) | CYP3A4ALDH1A1MAPTCYP2C9SMN1; SMN2 | |
| SCHEMBL9639322 | 0.72 | CYP3A4 (0.36) | MEN1KMT2ACYP3A4CYP2C9KDM4E | |
| Bromide SCHEMBL10393939 | 0.72 | CYP3A4 (0.36) | MEN1KMT2ACYP3A4CYP2C9KDM4E | |
| SCHEMBL4664940 | 0.64 | — | — | |
| SCHEMBL6204871 | 0.62 | CES2 (0.44) | MEN1KMT2ACYP3A4ALDH1A1LMNA | |
| SCHEMBL5731352 | 0.61 | CES2 (0.41) | MEN1KMT2ACYP3A4ALDH1A1MAPT | |
| SCHEMBL25135257 | 0.60 | CA1 (0.32) | CYP3A4ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL29591877 | 0.60 | PDE2A (0.54) | MEN1KMT2ACYP3A4ALDH1A1MAPT | |
| SCHEMBL5485147 | 0.60 | PDE2A (0.54) | MEN1KMT2ACYP3A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349609-B1 | AMINOACID ESTERS, PROCESS FOR THEIR MANUFACTURE AND THEIR USE | Dr. Willmar Schwabe GmbH & Co. (DE) | 1992-08-05 | — | — | EP | disclosed |
| US-4965283-A | Anticonvillsants, antiepileptic agents | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1990-10-23 | — | — | US | disclosed |
| EP-0349609-A1 | AMINOACID ESTERS, PROCESS FOR THEIR MANUFACTURE AND THEIR USE | Dr. Willmar Schwabe GmbH & Co. (DE) | 1990-01-10 | — | — | EP | disclosed |
| WO-1989004310-A1 | AMINOACID ESTERS, PROCESS FOR THEIR MANUFACTURE AND THEIR USE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1989-05-18 | — | — | WO | disclosed |