Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639626 | 0.87 | PTPN1 (0.41) | HDAC1PRKCIPTPN1PTPN11LMNA | |
| SCHEMBL9638964 | 0.86 | PTGS2 (0.49) | HDAC1PRKCILMNAMAPTXBP1 | |
| SCHEMBL9639008 | 0.79 | HDAC1 (0.47) | HDAC1PRKCIPTPN1PTPN11LMNA | |
| SCHEMBL9639029 | 0.79 | PTPN1 (0.55) | PRKCIPTPN1PTPN11LMNAMAPT | |
| SCHEMBL9639605 | 0.78 | PRKCI (0.46) | PRKCIPTPN1PTPN11MAPTKDM4E | |
| SCHEMBL1173779 | 0.78 | PTPN1 (0.47) | AKR1C2AKR1C1PRKCIPTPN1PTPN11 | |
| SCHEMBL9638915 | 0.77 | CA12 (0.45) | PRKCIPTPN1PTPN11LMNAMAPT | |
| SCHEMBL9640277 | 0.77 | HSP90AB1 (0.49) | SERPINE1PTPN1PTPN11LMNAMAPT | |
| SCHEMBL9638961 | 0.77 | HDAC1 (0.70) | HDAC1SERPINE1PTPN1LMNAMAPT | |
| SCHEMBL8430837 | 0.75 | BCL2 (0.59) | HDAC1PTPN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227487-B1 | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |