Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962764 | 0.91 | USP2 (0.33) | USP2KMT2AIRAK4 | |
| SCHEMBL4553829 | 0.85 | IRAK4 (0.36) | USP2KMT2AIRAK4 | |
| SCHEMBL966800 | 0.84 | USP2 (0.36) | USP2KMT2A | |
| SCHEMBL963454 | 0.80 | POLB (0.33) | — | |
| SCHEMBL965948 | 0.80 | LMNA (0.34) | USP2KMT2A | |
| SCHEMBL963813 | 0.79 | KDM4E (0.33) | — | |
| SCHEMBL966982 | 0.75 | PHGDH (0.34) | USP2KMT2A | |
| SCHEMBL5117304 | 0.74 | ENPP3 (0.33) | — | |
| SCHEMBL963201 | 0.74 | NPC1 (0.41) | KMT2A | |
| Potassium Ion SCHEMBL967016 | 0.73 | IRAK4 (0.32) | USP2KMT2AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009384-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009384-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | PPARA, PPARD, PPARG | USP2 4289/4885KMT2A 2017/4885IRAK4 873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.