Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | CPA3 | P15088 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833268 | 1.00 | CYP1A2 (0.45) | CYP1A2MAPTFAAHCPA1TRPA1 | |
| SCHEMBL9640676 | 1.00 | CYP1A2 (0.45) | CYP1A2MAPTFAAHCPA1TRPA1 | |
| SCHEMBL9709042 | 0.78 | CYP1A2 (0.46) | CYP1A2FAAHCPA1TRPA1CPB1 | |
| SCHEMBL9640670 | 0.77 | CYP1A2 (0.39) | CYP1A2MAPTFAAHSLC6A2SLC6A4 | |
| SCHEMBL22259891 | 0.70 | — | — | |
| SCHEMBL25339415 | 0.69 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21103045 | 0.69 | CYP1A2 (0.35) | CYP1A2TRPA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22260324 | 0.69 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20833040 | 0.69 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22461896 | 0.69 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287042-B1 | 2-SULPHINYL-ACETYL-1,3-THIAZOLIDINES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-09-16 | — | — | EP | disclosed |
| US-4849437-A | 2-sulphinyl-acetyl-1,3-thiazolidines, their preparation and pharmaceutical compositions | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-07-18 | — | — | US | disclosed |
| EP-0287042-A1 | 2-Sulphinyl-acetyl-1,3-thiazolidines, their preparation and pharmaceutical compositions | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1988-10-19 | — | — | EP | disclosed |