Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833268 | 0.78 | CYP1A2 (0.45) | CYP1A2FAAHCPA1CPB1CPA3 | |
| SCHEMBL9640676 | 0.78 | CYP1A2 (0.45) | CYP1A2FAAHCPA1CPB1CPA3 | |
| SCHEMBL9640267 | 0.78 | CYP1A2 (0.45) | CYP1A2FAAHCPA1CPB1CPA3 | |
| SCHEMBL9709146 | 0.74 | HDAC2 (0.40) | CYP1A2ALDH1A1 | |
| SCHEMBL27832973 | 0.72 | CPN1 (0.45) | EPHX1ALPIPKMPTGS1XIAP | |
| SCHEMBL4180733 | 0.72 | EPHX1 (0.51) | CYP1A2EPHX1ALPIPKMPTGS1 | |
| SCHEMBL10411479 | 0.72 | ALPI (0.49) | CYP1A2FAAHALPIPKMPTGS1 | |
| SCHEMBL10411481 | 0.72 | ALPI (0.49) | CYP1A2FAAHALPIPKMPTGS1 | |
| SCHEMBL9640670 | 0.71 | CYP1A2 (0.39) | CYP1A2FAAH | |
| SCHEMBL4156781 | 0.70 | EPHX1 (0.43) | EPHX1ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020665-A1 | THIAZOLIDINE DERIVATIVES AND THEIR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | disclosed |