Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602349 | 0.99 | HTT (0.42) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL542764 | 0.95 | HTT (0.38) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL5013003 | 0.88 | FUT7 (0.34) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL5014104 | 0.88 | GABRA1 (0.40) | — | |
| Pyrophosphoric Acid SCHEMBL472731 | 0.87 | S1PR1 (0.40) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL997214 | 0.81 | S1PR1 (0.40) | TNNC1S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL472730 | 0.80 | S1PR1 (0.41) | S1PR1S1PR4S1PR3S1PR5S1PR2 | |
| SCHEMBL6058927 | 0.79 | THRA (0.45) | THRB | |
| SCHEMBL98963 | 0.79 | THRA (0.45) | THRB | |
| SCHEMBL7529783 | 0.79 | THRA (0.45) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5103035-A | Process for preparing bis(alkylphenyl)pentaerythritol diphosphites | ETHYL CORPORATION (US) | 1992-04-07 | — | — | US | disclosed |