Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640804 | 0.93 | TSHR (0.54) | TSHRRECQLHDAC3HDAC1HDAC2 | |
| SCHEMBL5425398 | 0.87 | TSHR (0.64) | TSHRRECQLPOLBSLC6A2SLC6A4 | |
| SCHEMBL12786257 | 0.87 | TSHR (0.64) | TSHRRECQLPOLBSLC6A2SLC6A4 | |
| SCHEMBL893965 | 0.87 | TSHR (0.59) | TSHRRECQLPOLBRORCSLC6A2 | |
| SCHEMBL1608155 | 0.87 | TSHR (0.59) | TSHRRECQLPOLBRORCSLC6A2 | |
| SCHEMBL9597865 | 0.87 | TSHR (0.59) | TSHRRECQLPOLBRORCSLC6A2 | |
| Hydrochloric Acid SCHEMBL9623842 | 0.85 | TSHR (0.62) | TSHRRECQLPOLBSLC6A2SLC6A4 | |
| SCHEMBL21227439 | 0.84 | HDAC3 (0.47) | TSHRRECQLHDAC3HDAC1HDAC2 | |
| SCHEMBL725217 | 0.83 | ALDH1A1 (0.53) | TSHRRECQLBCHEPOLBKDM4E | |
| SCHEMBL2310169 | 0.83 | TSHR (0.51) | TSHRRECQLBCHEPOLBSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128408-A | Quaternized amino polyurethane- or polyurethaneurea-polysiloxanes treated with heparin | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1992-07-07 | — | — | US | disclosed |