Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640535 | 0.93 | TSHR (0.51) | TSHRRECQLPOLBRORCMEN1 | |
| SCHEMBL12786257 | 0.90 | TSHR (0.64) | TSHRRECQLPOLBMEN1KMT2A | |
| SCHEMBL9597865 | 0.90 | TSHR (0.59) | TSHRRECQLPOLBRORCMEN1 | |
| SCHEMBL1608155 | 0.90 | TSHR (0.59) | TSHRRECQLPOLBRORCMEN1 | |
| SCHEMBL5425398 | 0.90 | TSHR (0.64) | TSHRRECQLPOLBMEN1KMT2A | |
| SCHEMBL893965 | 0.90 | TSHR (0.59) | TSHRRECQLPOLBRORCMEN1 | |
| Hydrochloric Acid SCHEMBL9623842 | 0.89 | TSHR (0.62) | TSHRRECQLPOLBMEN1KMT2A | |
| SCHEMBL17941715 | 0.86 | ALDH1A1 (0.53) | TSHRRECQLHTTPOLBMEN1 | |
| SCHEMBL2310169 | 0.86 | TSHR (0.51) | TSHRRECQLPOLBMEN1KMT2A | |
| SCHEMBL725217 | 0.86 | ALDH1A1 (0.53) | TSHRRECQLHTTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128408-A | Quaternized amino polyurethane- or polyurethaneurea-polysiloxanes treated with heparin | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1992-07-07 | — | — | US | disclosed |