Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640909 | 0.85 | NPSR1 (0.48) | TSHRTDP1KDM4EMAPTMEN1 | |
| SCHEMBL9639513 | 0.82 | TSHR (0.44) | TSHRTDP1KDM4EMAPTMEN1 | |
| SCHEMBL11175512 | 0.76 | TSHR (0.57) | TSHRTDP1KDM4EMAPTMEN1 | |
| SCHEMBL9641018 | 0.76 | MAPK8 (0.44) | TSHRTDP1KDM4EMAPTMEN1 | |
| SCHEMBL11169559 | 0.71 | TSHR (0.50) | TSHRTDP1KDM4EMAPTMEN1 | |
| SCHEMBL2741119 | 0.69 | TDP1 (0.64) | TSHRTDP1MAPTMEN1KMT2A | |
| SCHEMBL27571535 | 0.69 | MAPT (0.40) | TSHRTDP1KDM4EMAPTMEN1 | |
| SCHEMBL17254246 | 0.69 | ALDH1A1 (0.54) | KDM4EHPGDNPSR1ALDH1A1RECQL | |
| SCHEMBL2339204 | 0.69 | MAPT (0.60) | TSHRTDP1KDM4EMAPTMEN1 | |
| SCHEMBL2338559 | 0.69 | MAPT (0.66) | TSHRTDP1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244360-B1 | SUBSTITUTED PYRIMIDINES | CIBA-GEIGY AG (CH) | 1992-08-19 | — | — | EP | disclosed |
| EP-0273862-B1 | NON-AQUEOUS LIQUID ECTOPARASITICIDAL POUR-ON FORMULATION | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | disclosed |
| US-4783468-A | Insecticidal 5-pyrimidine carbonitriles | CIBA-GEIGY CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |
| EP-0273862-A2 | Non-aqueous liquid ectoparasiticidal pour-on formulation | CIBA-GEIGY AG (CH) | 1988-07-06 | — | — | EP | disclosed |
| EP-0244360-A2 | Substituted pyrimidines | CIBA-GEIGY AG (CH) | 1987-11-04 | — | — | EP | disclosed |