Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640682 | 0.85 | TSHR (0.57) | NPSR1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL810841 | 0.73 | NPSR1 (0.49) | NPSR1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9639513 | 0.73 | TSHR (0.44) | NPSR1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8986160 | 0.71 | MEN1 (0.60) | NPSR1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL19734642 | 0.68 | MEN1 (0.53) | NPSR1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL967156 | 0.68 | ALDH1A1 (0.59) | NPSR1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL11175512 | 0.67 | TSHR (0.57) | NPSR1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9641018 | 0.67 | MAPK8 (0.44) | NPSR1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10989504 | 0.66 | PGK1 (0.36) | KMT2AKDM4EMAPTHTTALOX15 | |
| SCHEMBL6247068 | 0.65 | KDM4E (0.76) | NPSR1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244360-B1 | SUBSTITUTED PYRIMIDINES | CIBA-GEIGY AG (CH) | 1992-08-19 | — | — | EP | disclosed |
| EP-0273862-B1 | NON-AQUEOUS LIQUID ECTOPARASITICIDAL POUR-ON FORMULATION | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | disclosed |
| US-4783468-A | Insecticidal 5-pyrimidine carbonitriles | CIBA-GEIGY CORPORATION (US) | 1988-11-08 | — | — | US | disclosed |