Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9640715 | 1.00 | KDM4E (0.46) | KDM4EGLAMEN1KMT2APOLB | |
| SCHEMBL9640701 | 0.83 | SMN1; SMN2 (0.50) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL9640703 | 0.83 | SMN1; SMN2 (0.50) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL9640731 | 0.83 | ALDH1A1 (0.46) | MEN1KMT2ACDC25BMAPTALDH1A1 | |
| SCHEMBL9640736 | 0.83 | ALDH1A1 (0.46) | MEN1KMT2ACDC25BMAPTALDH1A1 | |
| SCHEMBL9640551 | 0.78 | TSHR (0.56) | KDM4EGLAMEN1KMT2APOLB | |
| SCHEMBL305920 | 0.78 | TSHR (0.55) | KDM4EGLAMEN1KMT2APOLB | |
| SCHEMBL305921 | 0.78 | TSHR (0.55) | KDM4EGLAMEN1KMT2APOLB | |
| SCHEMBL306855 | 0.78 | TSHR (0.55) | KDM4EGLAMEN1KMT2APOLB | |
| SCHEMBL305927 | 0.75 | ALDH1A1 (0.44) | KDM4EGLAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081122-A | Antiglaucoma compositions containing 4-arylcarbonyl-1-(4-morpholinyl)-lower-alkyl)-1H-indoles and method of use thereof | STERLING DRUG INC. (US) | 1992-01-14 | — | — | US | disclosed |