⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1485707 | 0.78 | — | — | |
| SCHEMBL1485960 | 0.74 | LMNA (0.36) | — | |
| SCHEMBL14541567 | 0.73 | — | — | |
| SCHEMBL5880671 | 0.72 | TP53 (0.37) | — | |
| SCHEMBL14028651 | 0.71 | — | — | |
| SCHEMBL13348002 | 0.71 | — | — | |
| SCHEMBL21086719 | 0.71 | — | — | |
| SCHEMBL1485715 | 0.71 | — | — | |
| SCHEMBL15221247 | 0.71 | — | — | |
| SCHEMBL1485711 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162522-A | Method for producing cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| US-4908444-A | Method of producing cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-13 | — | — | US | disclosed |
| EP-0354538-A2 | Method for producing cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1990-02-14 | — | — | EP | disclosed |
| EP-0230972-A2 | Method of producing cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1987-08-05 | — | — | EP | disclosed |
| US-4520194-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-05-28 | — | — | US | disclosed |
| US-4510138-A | 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]cephalosporin derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-04-09 | — | — | US | disclosed |
| US-4323676-A | Process for preparing cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4308381-A | Cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4278671-A | ANTIBIOTICS, BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-07-14 | — | — | US | disclosed |
| US-4245088-A | Novel 3-acyloxymethyl-cephem compounds useful as intermediates for preparing cephalosporin antibiotics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-01-13 | — | — | US | disclosed |
| US-4224441-A | Derivatives of 7-aminocephalosporanic acid | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-09-23 | — | — | US | disclosed |
| US-4182866-A | CEPHALOSPORINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-01-08 | — | — | US | disclosed |
| US-4166178-A | 3-ACYLOXYMETHYL-CEPHEM COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4145540-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4011214-A | 3-(MORPHOLINOALKOXYIMINOMETHYL)CEPHEM COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-03-08 | — | — | US | disclosed |
| US-3989685-A | FROM PENICILLIN-1-OXIDE | SHINOGI & CO., LTD. (JA) | 1976-11-02 | — | — | US | disclosed |
| US-3984403-A | PAINLESS INTRAMUSCULAR INJECTION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-10-05 | — | — | US | disclosed |