SCHEMBL5880671

SCHEMBL5880671

O=C(O)CNC1=CC=CCC1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.37
RAB9A P51151 1/20 0.37
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10581307 0.84 EPHX2 (0.33) EPHX2
SCHEMBL7596987 0.75 EPHX2 (0.36) EPHX2
SCHEMBL28330036 0.74
SCHEMBL21086719 0.73
SCHEMBL1485707 0.72
SCHEMBL9640756 0.72
SCHEMBL14397938 0.69 EPHX2 (0.35) EPHX2
SCHEMBL17146854 0.69 EPHX2 (0.38) RAB9AEPHX2
SCHEMBL1485960 0.69 LMNA (0.36)
SCHEMBL15221247 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0984982-A1 LH-RH PEPTIDE ANALOGUES, THEIR USES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM LABORATOIRE THERAMEX (MC) 2000-03-15 EP claimed
US-4073687-A PENICILLINS OR CEPHALOSPORINS SHIONOGI & CO., LTD. (JA) 1978-02-14 US claimed
EP-3991983-A1 ORIGINAL PLATE FOR ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE, METHOD FOR FABRICATING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM Corporation (JP) 2022-05-04 EP disclosed
EP-3900942-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING LITHOGRAPHIC PRINTING PLATE, AND LITHOGRAPHIC PRINTING METHOD FUJIFILM Corporation (JP) 2021-10-27 EP disclosed
US-7048907-B2 Synthesis, compositions and methods for the measurement of the concentration of stable-isotope labeled compounds in life forms and life form excretory products BIOPHYSICS ASSAY LABORATORY, INC. (US) 2006-05-23 US disclosed
US-20060067881-A1 Synthesis, compositions and methods for the measurement of the concentration of stable-isotope labeled compounds in life forms and life form excretory products BIOPHYSICS ASSAY LABORATORY, INC. 2006-03-30 US disclosed
EP-1399170-A2 CHELATES OF METALS WHICH CAN BE ACTIVATED BY NEUTRONS AND THEIR USE FOR THE MEASUREMENT OF LABELED SPECIMENS Biophysics Assay Laboratory, Inc. (US) 2004-03-24 EP disclosed
US-20030059368-A1 Synthesis, compositions and methods for the measurement of the concentration of stable-isotope labeled compounds in life forms and life form excretory products BIOPAL, INC. 2003-03-27 US disclosed
WO-2002062397-A2 CHELATES OF METALS WHICH CAN BE ACTIVATED BY NEUTRONS AND THEIR USE FOR THE MEASUREMENT OF LABELED SPECIMENS BIOPHYSICS ASSAY LABORATORY, INC. (US) 2002-08-15 WO disclosed
EP-1117420-A1 PHARMACEUTICAL COMPOSITIONS BASED ON ALPHA-CYCLODEXTRIN FOR THE ORAL ADMINISTRATION OF LH-RH ANALOGUES LABORATOIRE THERAMEX S.A. (MC) 2001-07-25 EP disclosed
WO-2000018423-A1 PHARMACEUTICAL COMPOSITIONS BASED ON ALPHA-CYCLODEXTRIN FOR THE ORAL ADMINISTRATION OF LH-RH ANALOGUES LABORATOIRE THERAMEX (MC) 2000-04-06 WO disclosed
EP-0984982-A1 LH-RH PEPTIDE ANALOGUES, THEIR USES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM LABORATOIRE THERAMEX (MC) 2000-03-15 EP disclosed
WO-1998055505-A1 LH-RH PEPTIDE ANALOGUES, THEIR USES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM LABORATOIRE THERAMEX (MC) 1998-12-10 WO disclosed
US-4073687-A PENICILLINS OR CEPHALOSPORINS SHIONOGI & CO., LTD. (JA) 1978-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060067881-A1 Synthesis, compositions and methods for the measurement of the concentration of stable-isotope labeled compounds in life forms and life form excretory products ATP6V1B1, REN, GLS TP53 3580/4885RAB9A 562/4885GRIN2D 4775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.