Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557150 | 0.88 | — | — | |
| SCHEMBL6439988 | 0.83 | ALDH1A1 (0.35) | TAAR1ALDH1A1TSHRLMNAGAA | |
| SCHEMBL19328661 | 0.82 | NR5A1 (0.43) | HDAC1HDAC11HDAC8HDAC6ALDH1A1 | |
| SCHEMBL9510234 | 0.82 | NR5A1 (0.43) | HDAC1HDAC11HDAC8HDAC6ALDH1A1 | |
| SCHEMBL562517 | 0.82 | NR5A1 (0.43) | HDAC1HDAC11HDAC8HDAC6ALDH1A1 | |
| SCHEMBL161224 | 0.82 | NR5A1 (0.43) | HDAC1HDAC11HDAC8HDAC6ALDH1A1 | |
| SCHEMBL5594284 | 0.82 | ADRA2A (0.32) | TAAR1KCNA3 | |
| SCHEMBL5832088 | 0.82 | NR5A1 (0.43) | HDAC1HDAC11HDAC8HDAC6ALDH1A1 | |
| SCHEMBL905397 | 0.82 | NR5A1 (0.43) | HDAC1HDAC11HDAC8HDAC6ALDH1A1 | |
| SCHEMBL6240761 | 0.82 | NR5A1 (0.43) | HDAC1HDAC11HDAC8HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328984-B1 | PROCESS FOR THE PREPARATON OF THIOPHENE ETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-23 | — | — | EP | disclosed |
| US-4931568-A | REACTING C1-C3 ALYKYLOXYTHIOPHENES WITH ALCOHOL; MONOMERS FOR ELECTROCONDUCTIVE POLYMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-05 | — | — | US | disclosed |
| CN-1035291-A | The preparation method of thiophenethers | HOECHST AG (DE) | 1989-09-06 | — | — | CN | disclosed |
| EP-0328984-A1 | Process for the preparaton of thiophene ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | disclosed |