Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10859148 | 0.90 | ALDH1A1 (0.40) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL9640044 | 0.90 | ALDH1A1 (0.40) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL10390567 | 0.89 | ALDH1A1 (0.42) | POLBALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL9641293 | 0.88 | TDP1 (0.43) | POLBALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL10390590 | 0.84 | TDP1 (0.42) | POLBALDH1A1MAPTHPGDTDP1 | |
| Ammonia Solution, Strong SCHEMBL27921882 | 0.83 | ALDH1A1 (0.41) | POLBALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL10390385 | 0.83 | GAA (0.44) | POLBALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL7852848 | 0.82 | ATM (0.43) | POLBALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9640607 | 0.82 | ALDH1A1 (0.42) | POLBALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL10739299 | 0.82 | ALDH1A1 (0.42) | POLBALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243686-B1 | BETA-LACTAM COMPOUNDS, AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5093328-A | Carbapenicillin antibiotics | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0243686-A2 | Beta-lactam compounds, and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-04 | — | — | EP | disclosed |