Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10861535 | 1.00 | TDP1 (0.44) | TDP1ATMPOLBALDH1A1MAPT | |
| SCHEMBL10390151 | 1.00 | TDP1 (0.44) | TDP1ATMPOLBALDH1A1MAPT | |
| SCHEMBL9641293 | 0.89 | TDP1 (0.43) | TDP1ATMPOLBALDH1A1MAPT | |
| SCHEMBL10390385 | 0.88 | GAA (0.44) | TDP1ATMPOLBALDH1A1MAPT | |
| SCHEMBL10390590 | 0.87 | TDP1 (0.42) | TDP1ATMPOLBALDH1A1MAPT | |
| SCHEMBL9519940 | 0.87 | TDP1 (0.42) | TDP1ATMPOLBALDH1A1MAPT | |
| SCHEMBL7854717 | 0.87 | TDP1 (0.50) | TDP1ATMPOLBALDH1A1MAPT | |
| SCHEMBL6771895 | 0.86 | HTR2A (0.42) | TDP1ATMPOLBALDH1A1MAPT | |
| SCHEMBL9640607 | 0.85 | ALDH1A1 (0.42) | TDP1ATMPOLBALDH1A1MAPT | |
| SCHEMBL10739299 | 0.85 | ALDH1A1 (0.42) | TDP1ATMPOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243686-B1 | BETA-LACTAM COMPOUNDS, AND THEIR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-07-15 | — | — | EP | disclosed |
| US-5093328-A | Carbapenicillin antibiotics | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-03-03 | — | — | US | disclosed |
| US-4962103-A | MICROBIOCIDES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0182213-B1 | CARBAPENEM COMPOUNDS AND PRODUCTION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1990-09-26 | — | — | EP | disclosed |
| EP-0243686-A2 | Beta-lactam compounds, and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1987-11-04 | — | — | EP | disclosed |
| EP-0182213-A1 | Carbapenem compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1986-05-28 | — | — | EP | disclosed |