SCHEMBL9640951

SCHEMBL9640951

CC(O)CN(C)c1ccc(C(=O)c2ccc(N(C)CC(C)O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
HPGD P15428 6/20 0.53
MAPT P10636 3/20 0.53
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.47
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
PKM P14618 1/20 0.40
ABCB1 P08183 1/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10847593 0.83 AKR1C3 (0.53) ALDH1A1HPGDRAB9ANPC1LMNA
SCHEMBL11570799 0.83 HPGD (0.50) ALDH1A1HPGDMAPTRAB9ANPC1
SCHEMBL17576039 0.80 CA12 (0.56) ALDH1A1HPGDMAPTRAB9ANPC1
SCHEMBL3880036 0.79 ALDH1A1 (0.44) ALDH1A1MAPTRAB9AMEN1KMT2A
SCHEMBL11571914 0.78 HPGD (0.46) ALDH1A1HPGDMAPTRAB9ANPC1
SCHEMBL4540287 0.77 RAB9A (0.56) ALDH1A1HPGDMAPTRAB9ANPC1
SCHEMBL1956071 0.76 KDM4E (0.43) ALDH1A1LMNATP53SMN1; SMN2KDM4E
SCHEMBL7245024 0.76 KDM4E (0.43) ALDH1A1LMNATP53SMN1; SMN2KDM4E
SCHEMBL7249398 0.76 KDM4E (0.43) ALDH1A1LMNATP53SMN1; SMN2KDM4E
SCHEMBL82487 0.76 HPGD (0.61) ALDH1A1HPGDMAPTRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0331007-B1 LIGHT-SENSITIVE RECORDING MATERIALS FOR THE MANUFACTURE OF SCRATCH-RESISTANT INTAGLIO PRINTING FORMES BASF Aktiengesellschaft (DE) 1992-09-02 EP disclosed
US-4994348-A Light-sensitive recording materials for producing mar-resistant intaglio printing plates BASF AKTIENGESELLSCHAFT (DE) 1991-02-19 US disclosed
EP-0331007-A2 Light-sensitive recording materials for the manufacture of scratch-resistant intaglio printing formes BASF Aktiengesellschaft (DE) 1989-09-06 EP disclosed
US-4550072-A Photosensitive recording materials containing particles for the production of abrasion-resistant gravure printing plates, and the production of gravure printing plates using these recording materials BASF AKTIENGESELLSCHAFT (DE) 1985-10-29 US disclosed
US-4548894-A Photosensitive recording materials for the production of abrasion-resistant and scratch-resistant gravure printing plates comprising particles BASF AKTIENGESELLSCHAFT (DE) 1985-10-22 US disclosed
US-4147604-A PRINTING INKS, COATINGS, PRINTING PLATES BASF AKTIENGESELLSCHAFT (DE) 1979-04-03 US disclosed
EP-0000342-A1 Photopolymerisable binders BASF Aktiengesellschaft (DE) 1979-01-24 EP disclosed