Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.35 |
| ▸ | THRA | P10827 | 6/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642599 | 1.00 | THRB (0.35) | THRBTHRACNR1CNR2CYP2C9 | |
| SCHEMBL9643617 | 0.96 | CNR1 (0.37) | THRBTHRACNR1CNR2CYP2C9 | |
| SCHEMBL9642619 | 0.93 | THRB (0.38) | THRBTHRACNR1CNR2CYP2C9 | |
| SCHEMBL9642842 | 0.93 | THRB (0.38) | THRBTHRACNR1CNR2CYP2C9 | |
| SCHEMBL9643144 | 0.92 | PPARG (0.36) | THRBTHRACNR1CNR2CYP2C9 | |
| SCHEMBL9643118 | 0.92 | PPARG (0.36) | THRBTHRACNR1CNR2CYP2C9 | |
| SCHEMBL9642526 | 0.92 | POLM (0.40) | THRBTHRACNR1CNR2EPHX2 | |
| SCHEMBL9642974 | 0.88 | GSTA1 (0.38) | THRBTHRACNR1CNR2CYP2C9 | |
| SCHEMBL9641826 | 0.88 | GSTA1 (0.38) | THRBTHRACNR1CNR2CYP2C9 | |
| SCHEMBL9642345 | 0.85 | CNR1 (0.38) | THRBTHRACNR1CNR2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |