Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642163 | 1.00 | L3MBTL1 (0.46) | L3MBTL1CNR1CNR2KMT2AMEN1 | |
| SCHEMBL9642136 | 0.86 | TP53 (0.49) | KMT2AKDM4EMAPTTP53ABCB11 | |
| SCHEMBL9643375 | 0.80 | MAPT (0.45) | L3MBTL1KDM4EMAPTTP53ABCB11 | |
| SCHEMBL9643595 | 0.80 | MAPT (0.45) | L3MBTL1KDM4EMAPTTP53ABCB11 | |
| SCHEMBL9642492 | 0.79 | TP53 (0.46) | KMT2AKDM4EMAPTTP53ABCB11 | |
| SCHEMBL9642932 | 0.79 | TP53 (0.46) | KMT2AKDM4EMAPTTP53ABCB11 | |
| SCHEMBL9643412 | 0.74 | ABCB11 (0.50) | KMT2AMEN1MAPTABCB11ESR1 | |
| SCHEMBL9643394 | 0.74 | ABCB11 (0.50) | KMT2AMEN1MAPTABCB11ESR1 | |
| SCHEMBL9642621 | 0.73 | ABCB11 (0.48) | KMT2AKDM4ERECQLABCB11ALDH1A1 | |
| SCHEMBL9642233 | 0.73 | ABCB11 (0.60) | MAPTABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |