Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642845 | 0.91 | ABCB11 (0.46) | L3MBTL1MAPK1MAPTKDM4EABCB11 | |
| SCHEMBL9641816 | 0.87 | ABCB11 (0.37) | L3MBTL1MAPK1MAPTABCB11TP53 | |
| SCHEMBL9642104 | 0.85 | KMT2A (0.40) | L3MBTL1MAPK1MAPTKDM4EABCB11 | |
| SCHEMBL9641974 | 0.85 | KMT2A (0.40) | L3MBTL1MAPK1MAPTKDM4EABCB11 | |
| SCHEMBL9643362 | 0.83 | ABCB11 (0.58) | L3MBTL1MAPK1MAPTKDM4EABCB11 | |
| SCHEMBL9643532 | 0.83 | ABCB11 (0.58) | L3MBTL1MAPK1MAPTKDM4EABCB11 | |
| SCHEMBL9641814 | 0.82 | ABCB11 (0.38) | L3MBTL1MAPK1MAPTKDM4EABCB11 | |
| SCHEMBL9643019 | 0.82 | ABCB11 (0.38) | L3MBTL1MAPK1MAPTKDM4EABCB11 | |
| SCHEMBL9643938 | 0.82 | ABCB11 (0.38) | L3MBTL1MAPK1MAPTKDM4EABCB11 | |
| SCHEMBL9643850 | 0.79 | MAPT (0.41) | L3MBTL1MAPK1MAPTKDM4EABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |