Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.39 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643362 | 1.00 | ABCB11 (0.58) | ABCB11LMNAMAPTKMT2ANPSR1 | |
| SCHEMBL9643337 | 0.90 | ABCB11 (0.70) | ABCB11LMNAMAPTKMT2AMEN1 | |
| SCHEMBL9642973 | 0.83 | L3MBTL1 (0.43) | ABCB11LMNAMAPTKMT2ANPSR1 | |
| SCHEMBL9627670 | 0.82 | ABCB11 (0.59) | ABCB11MAPTMAOBL3MBTL1KDM4E | |
| SCHEMBL9627563 | 0.82 | ABCB11 (0.63) | ABCB11MAPTMAOBL3MBTL1KDM4E | |
| SCHEMBL9643229 | 0.82 | ABCB11 (0.59) | ABCB11MAPTKMT2AMEN1MAOB | |
| SCHEMBL9642519 | 0.82 | ABCB11 (0.59) | ABCB11MAPTKMT2AMEN1MAOB | |
| SCHEMBL9641671 | 0.81 | ABCB11 (0.59) | ABCB11MAPTMAOBKDM4E | |
| SCHEMBL9643471 | 0.81 | ABCB11 (0.59) | ABCB11MAPTMAOBKDM4E | |
| SCHEMBL9643182 | 0.80 | ABCB11 (0.54) | ABCB11LMNAMAPTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |