Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 7/20 | 0.41 |
| ▸ | PGR | P06401 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.40 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643024 | 1.00 | KMT2A (0.41) | KMT2ACTDSP1NR1I2PGRPPARG | |
| SCHEMBL10639008 | 0.88 | NR1I2 (0.43) | KMT2ACTDSP1NR1I2PGRPPARG | |
| SCHEMBL10638997 | 0.88 | NR1I2 (0.43) | KMT2ACTDSP1NR1I2PGRPPARG | |
| Bromide SCHEMBL10835276 | 0.86 | NR1I2 (0.49) | KMT2ACTDSP1NR1I2PGRPPARG | |
| Iodide SCHEMBL10959262 | 0.86 | KMT2A (0.49) | KMT2ACTDSP1NR1I2PGRPPARG | |
| Bromide SCHEMBL10955317 | 0.86 | KMT2A (0.47) | KMT2ACTDSP1NR1I2PGRPPARG | |
| SCHEMBL9643042 | 0.82 | — | — | |
| SCHEMBL9643776 | 0.81 | CTDSP1 (0.47) | KMT2ACTDSP1SLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9644311 | 0.81 | FAP (0.48) | KMT2ACTDSP1SLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10528959 | 0.80 | NR1I2 (0.56) | KMT2ANR1I2PGRPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168327-A2 | Cephalosporin compounds | MEIJI SEIKA KAISHA LTD. (JP) | 1986-01-15 | — | — | EP | claimed |
| EP-0168327-B1 | CEPHALOSPORIN COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-4791197-A | ANTIBIOTICS | SAKAGAMI KENJI (JP) | 1988-12-13 | — | — | US | disclosed |
| EP-0168327-A2 | Cephalosporin compounds | MEIJI SEIKA KAISHA LTD. (JP) | 1986-01-15 | — | — | EP | disclosed |