Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642923 | 1.00 | ABCB11 (0.43) | ABCB11EPHX2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9643614 | 0.93 | ABCB11 (0.45) | ABCB11EPHX2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9642038 | 0.93 | ABCB11 (0.45) | ABCB11EPHX2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9643262 | 0.92 | ABCB11 (0.44) | ABCB11EPHX2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9643429 | 0.92 | ABCB11 (0.44) | ABCB11EPHX2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9642891 | 0.92 | ABCB11 (0.50) | ABCB11ALDH1A1TDP1L3MBTL1MAPT | |
| SCHEMBL9643775 | 0.88 | ELANE (0.39) | ABCB11EPHX2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9644013 | 0.88 | ELANE (0.39) | ABCB11EPHX2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9642712 | 0.85 | ABCB11 (0.37) | ABCB11EPHX2ALOX15GAA | |
| SCHEMBL9643664 | 0.85 | ABCB11 (0.37) | ABCB11EPHX2ALOX15GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |