Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642698 | 1.00 | ABCB11 (0.50) | ABCB11KCNA3PTPN1LMNAHPGD | |
| SCHEMBL9642607 | 0.84 | ABCB11 (0.67) | ABCB11ALDH1A1HSD17B10 | |
| SCHEMBL9627496 | 0.78 | CASP3 (0.48) | ABCB11PTPN1HPGDMAOBALDH1A1 | |
| SCHEMBL29371684 | 0.77 | KDM4E (0.53) | ABCB11HPGDALDH1A1TSHRHSD17B10 | |
| SCHEMBL9643182 | 0.77 | ABCB11 (0.54) | ABCB11PTPN1LMNAHPGDMAOB | |
| SCHEMBL9642593 | 0.77 | ABCB11 (0.56) | ABCB11KCNA3HSD17B10 | |
| SCHEMBL9643136 | 0.77 | ABCB11 (0.56) | ABCB11KCNA3HSD17B10 | |
| SCHEMBL9643346 | 0.76 | SLC2A4 (0.43) | ABCB11LMNA | |
| SCHEMBL9641912 | 0.75 | ABCB11 (0.51) | ABCB11MAOBFFAR1 | |
| SCHEMBL9642811 | 0.74 | ABCB11 (0.54) | ABCB11KCNA3LMNAHPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |