Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642364 | 0.90 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL9643154 | 0.89 | CTSV (0.40) | SMN1; SMN2CTSVAKR1B1L3MBTL1ATM | |
| SCHEMBL9642159 | 0.86 | L3MBTL1 (0.39) | CTSVL3MBTL1GAAMAPTLMNA | |
| SCHEMBL10785617 | 0.85 | CTSV (0.36) | SMN1; SMN2CTSVAKR1B1L3MBTL1MEN1 | |
| SCHEMBL9642968 | 0.85 | KDM4E (0.47) | CTSVL3MBTL1KMT2APOLBGAA | |
| SCHEMBL9642281 | 0.82 | SMN1; SMN2 (0.35) | SMN1; SMN2L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL9641809 | 0.82 | SMN1; SMN2 (0.35) | SMN1; SMN2L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL9642362 | 0.81 | KDM4E (0.43) | SMN1; SMN2CTSVL3MBTL1MEN1KMT2A | |
| SCHEMBL9642407 | 0.81 | L3MBTL1 (0.41) | CTSVAKR1B1L3MBTL1MEN1KMT2A | |
| SCHEMBL9643523 | 0.81 | CTSV (0.37) | CTSVAKR1B1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |