SCHEMBL964384

SCHEMBL964384

CC(=N)OC(=O)[C@H](N)CCCN

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.42
DPP7 Q9UHL4 4/20 0.36
DPP4 P27487 2/20 0.36
DPP8 Q6V1X1 2/20 0.36
DPP9 Q86TI2 2/20 0.36
GNAI3 P08754 1/20 0.35
GNAO1 P09471 1/20 0.35
GNAI1 P63096 1/20 0.35
NOS3 P29474 4/20 0.34
NOS1 P29475 4/20 0.34
NOS2 P35228 4/20 0.34
CPB2 Q96IY4 3/20 0.33
CYP1A2 P05177 2/20 0.33
MEN1 O00255 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
PAOX Q6QHF9 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28698703 0.98 GSR (0.41) GSRDPP7DPP4DPP8DPP9
SCHEMBL965913 0.95 GSR (0.50) GSRDPP7DPP4DPP8DPP9
SCHEMBL535529 0.85 GSR (0.45) GSRDPP7DPP4DPP8DPP9
SCHEMBL997560 0.84 GSR (0.52) GSRDPP7DPP4DPP8DPP9
SCHEMBL29075853 0.84 GSR (0.52) GSRDPP7DPP4DPP8DPP9
SCHEMBL1537223 0.84 GSR (0.52) GSRDPP7DPP4DPP8DPP9
SCHEMBL8334818 0.81 GSR (0.39) GSRDPP7DPP4DPP8DPP9
SCHEMBL680614 0.80 GSR (0.59) GSRDPP7DPP4DPP8DPP9
SCHEMBL28091506 0.80 GSR (0.48) GSRDPP7DPP4DPP8DPP9
SCHEMBL52379 0.79 DPP7 (0.51) GSRDPP7DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2361967-A1 Gametes separation methods, compositions and uses thereof Assistance Publique - Hôpitaux de Paris (FR) 2011-08-31 EP claimed
CN-104940126-A Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders OTONOMY INC 2015-09-30 CN disclosed
CN-102105133-B Controlled release otic structure modulating and innate immune system modulating compositions and methods of treating otic disorders OTONOMY INC 2015-06-17 CN disclosed
CN-104491864-A Controlled Release Antimicrobial Compositions And Methods For The Treatment Of Otic Disorders OTONOMY INC 2015-04-08 CN disclosed
CN-104352429-A Controlled release antimicrobial compositions and methods for the treatment of otic disorders OTONOMY INC 2015-02-18 CN disclosed
US-8476196-B2 Control of harmful algal blooms by induction of programmed cell death UNIVERSITY OF SOUTH FLORIDA (US) 2013-07-02 US disclosed
EP-2361967-A1 Gametes separation methods, compositions and uses thereof Assistance Publique - Hôpitaux de Paris (FR) 2011-08-31 EP disclosed
US-20110028543-A1 Formulations and methods of using nitric oxide mimetics in cancer treatment QUEENS UNIVERSITY AT KINGSTON (CA) 2011-02-03 US disclosed
US-20110021357-A1 CONTROL OF HARMFUL ALGAL BLOOMS BY INDUCTION OF PROGRAMMED CELL DEATH UNIVERSITY OF SOUTH FLORIDA (US) 2011-01-27 US disclosed