Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SLC7A11 | Q9UPY5 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MPL | P40238 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26459353 | 0.85 | ATIC (1.00) | ATICRAB9AMAPK1ATML3MBTL1 | |
| SCHEMBL29159177 | 0.78 | SLC7A11 (0.50) | ATICRAB9AMAPTMAPK1HSP90AA1 | |
| SCHEMBL27622823 | 0.77 | SLC7A11 (0.62) | MAPTL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL25807355 | 0.76 | MAPT (0.67) | RAB9AMAPTMAPK1HSP90AA1KDM4E | |
| SCHEMBL24187557 | 0.75 | ATIC (0.81) | ATICRAB9AMAPTMAPK1ATM | |
| SCHEMBL21686790 | 0.75 | ATIC (0.64) | ATICMAPTMAPK1MEN1KMT2A | |
| SCHEMBL11819863 | 0.71 | ATIC (0.59) | ATICMAPTMAPK1L3MBTL1MEN1 | |
| SCHEMBL11800642 | 0.71 | SLC7A11 (0.49) | ATICRAB9AMAPTMAPK1KDM4E | |
| SCHEMBL28065859 | 0.71 | ATIC (0.57) | ATICMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL15274162 | 0.71 | ATIC (0.72) | ATICRAB9AMAPK1ATMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126329-A | Diagnosis of kidney disorders | NITTO BOSEKI CO., LTD. (JP) | 1992-06-30 | — | — | US | claimed |
| US-5126329-A | Diagnosis of kidney disorders | NITTO BOSEKI CO., LTD. (JP) | 1992-06-30 | — | — | US | disclosed |