Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642718 | 0.87 | ABCB11 (0.48) | ABCB11TP53TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL9642907 | 0.83 | ABCB11 (0.53) | ABCB11TSHRSMN1; SMN2KMT2AGAA | |
| SCHEMBL9643182 | 0.81 | ABCB11 (0.54) | ABCB11SMN1; SMN2GAARXRARXRB | |
| SCHEMBL9641799 | 0.81 | ABCB11 (0.41) | ABCB11TSHRSMN1; SMN2CYP3A4KMT2A | |
| SCHEMBL9643190 | 0.81 | ABCB11 (0.41) | ABCB11TSHRSMN1; SMN2CYP3A4KMT2A | |
| SCHEMBL9643876 | 0.79 | ABCB11 (0.47) | ABCB11TP53TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL9641843 | 0.79 | ABCB11 (0.41) | ABCB11SMN1; SMN2KMT2AESR1MEN1 | |
| SCHEMBL9644053 | 0.79 | ABCB11 (0.41) | ABCB11SMN1; SMN2KMT2AESR1MEN1 | |
| SCHEMBL9642731 | 0.79 | ABCB11 (0.42) | ABCB11TP53TSHRKMT2AGAA | |
| SCHEMBL9642172 | 0.78 | ABCB11 (0.50) | ABCB11TP53PARP10KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215622-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS AND PROCESS FOR MAKING THEM | SYNTEX (U.S.A.) INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4946845-A | STABLE ANTIINFLAMMATORY AGENTS, LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1990-08-07 | — | — | US | disclosed |
| US-4792556-A | LIPOXYGENASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0215622-A2 | Naphthalene anti-psoriatic agents and process for making them | SYNTEX (U.S.A.) INC. (US) | 1987-03-25 | — | — | EP | disclosed |