Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646265 | 0.76 | DAO (0.58) | ALOX5 | |
| SCHEMBL9645137 | 0.75 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9645129 | 0.74 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL31667227 | 0.73 | MEN1 (0.61) | MEN1KMT2AALOX5 | |
| SCHEMBL9645952 | 0.70 | ALOX5 (0.70) | ALOX5KDM4E | |
| SCHEMBL9645937 | 0.69 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9646328 | 0.69 | ALOX5 (0.45) | GAAALOX5 | |
| SCHEMBL2274341 | 0.69 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL28399982 | 0.69 | MPI (0.53) | MEN1PRNPKMT2AGAAALOX5 | |
| SCHEMBL826239 | 0.69 | PTGS1 (0.51) | MEN1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |