Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646328 | 0.80 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL9645129 | 0.76 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9646387 | 0.74 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9646265 | 0.74 | DAO (0.58) | ALOX5 | |
| SCHEMBL14469796 | 0.73 | ALOX5 (0.56) | ALOX5 | |
| SCHEMBL9645976 | 0.71 | TSPO (0.46) | FEN1 | |
| SCHEMBL30168125 | 0.70 | ALDH1A1 (0.59) | — | |
| SCHEMBL3150784 | 0.70 | ALDH1A1 (0.59) | — | |
| SCHEMBL14450645 | 0.70 | ALOX5 (0.51) | ALOX5 | |
| SCHEMBL4078853 | 0.70 | GRM5 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173496-A | Antiinflammatory agents | ICI PHARMA (FR) | 1992-12-22 | — | — | US | disclosed |
| EP-0284174-B1 | THERAPEUTIC PREPARATIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-29 | — | — | EP | disclosed |
| EP-0284174-A1 | Therapeutic preparations | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-09-28 | — | — | EP | disclosed |