Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28234782 | 0.83 | TDP1 (0.54) | TDP1CA1CA2CA9ITGA1 | |
| SCHEMBL8989782 | 0.83 | CA1 (0.46) | CYP3A4TDP1CA1CA2CA9 | |
| SCHEMBL18071075 | 0.83 | CA1 (0.46) | CYP3A4TDP1CA1CA2CA9 | |
| SCHEMBL11319350 | 0.81 | TDP1 (0.44) | CYP3A4CYP2C9CYP2C19TDP1CA1 | |
| SCHEMBL196710 | 0.79 | TDP1 (0.52) | TDP1CA1CA2CA9ITGA1 | |
| SCHEMBL30217935 | 0.79 | TDP1 (0.52) | TDP1CA1CA2CA9ITGA1 | |
| SCHEMBL11223463 | 0.77 | CA1 (0.48) | TDP1CA1CA2CA9ITGA1 | |
| SCHEMBL9646947 | 0.76 | CA1 (0.42) | CYP3A4TDP1CA1CA2CA9 | |
| SCHEMBL18068781 | 0.76 | NPC1 (0.42) | CYP3A4TDP1CA1CA2CA9 | |
| SCHEMBL8866123 | 0.75 | HSD11B1 (0.57) | CYP3A4CYP2C9CYP2C19TDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106960-A | Fiber-reactive and monoazo red and yellow dyes; color- and washfastness; formaldehyde-resistance; brightness | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0039306-B1 | AZO DYESTUFFS, METHODS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1984-01-11 | — | — | EP | disclosed |
| EP-0039306-A1 | Azo dyestuffs, methods for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-11-04 | — | — | EP | disclosed |