Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.48 |
| ▸ | CA2 | P00918 | 17/20 | 0.48 |
| ▸ | CA9 | Q16790 | 17/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 14/20 | 0.47 |
| ▸ | CA3 | P07451 | 5/20 | 0.47 |
| ▸ | CA4 | P22748 | 5/20 | 0.47 |
| ▸ | CA6 | P23280 | 5/20 | 0.47 |
| ▸ | CA7 | P43166 | 5/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.47 |
| ▸ | CA5A | P35218 | 4/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555741 | 0.87 | P2RX4 (0.46) | CA1CA2CA9SMN1; SMN2CA12 | |
| SCHEMBL11219712 | 0.81 | ALPL (0.37) | CA1CA2CA9SMN1; SMN2CA12 | |
| SCHEMBL11319350 | 0.81 | TDP1 (0.44) | CA1CA2CA9CA12CA3 | |
| SCHEMBL9646947 | 0.79 | CA1 (0.42) | CA1CA2CA9SMN1; SMN2CA12 | |
| SCHEMBL9645164 | 0.77 | CYP3A4 (0.44) | CA1CA2CA9ALDH1A1TDP1 | |
| SCHEMBL28234782 | 0.77 | TDP1 (0.54) | CA1CA2CA9ALDH1A1TDP1 | |
| SCHEMBL11555026 | 0.76 | CA2 (0.47) | CA1CA2CA9SMN1; SMN2CA12 | |
| SCHEMBL196710 | 0.75 | TDP1 (0.52) | CA1CA2CA9TDP1ITGA1 | |
| SCHEMBL30217935 | 0.75 | TDP1 (0.52) | CA1CA2CA9TDP1ITGA1 | |
| SCHEMBL11556382 | 0.75 | CYP2C9 (0.44) | CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341773-A | 2,4-Diamino-5-sulfamoylbenzene sulfonic acids and process for their manufacture | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-27 | — | — | US | disclosed |