Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.64 |
| ▸ | CA2 | P00918 | 9/20 | 0.64 |
| ▸ | CA4 | P22748 | 4/20 | 0.64 |
| ▸ | CA12 | O43570 | 3/20 | 0.64 |
| ▸ | CA6 | P23280 | 3/20 | 0.64 |
| ▸ | CA5A | P35218 | 3/20 | 0.64 |
| ▸ | CA7 | P43166 | 3/20 | 0.64 |
| ▸ | CA9 | Q16790 | 3/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.64 |
| ▸ | CA3 | P07451 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646464 | 0.86 | ALDH1A1 (0.46) | CA1CA2CA4CA12CA6 | |
| SCHEMBL10694360 | 0.85 | ALDH1A1 (0.50) | CA1CA2CA4CA12CA6 | |
| SCHEMBL11690411 | 0.84 | ALDH1A1 (0.47) | CA1CA2CA4CA12CA6 | |
| SCHEMBL11686242 | 0.83 | ALDH1A1 (0.51) | CA1CA2CA4CA12CA6 | |
| SCHEMBL11130676 | 0.83 | KDM4E (0.46) | CA1CA2CA4CA12CA6 | |
| SCHEMBL9646182 | 0.83 | CA12 (0.43) | CA1CA2CA4CA12CA6 | |
| SCHEMBL9645120 | 0.82 | CA1 (0.70) | CA1CA2CA4CA12CA6 | |
| SCHEMBL310205 | 0.79 | CA1 (1.00) | CA1CA2CA4CA12CA6 | |
| SCHEMBL29376122 | 0.79 | CA1 (1.00) | CA1CA2CA4CA12CA6 | |
| SCHEMBL30659050 | 0.79 | CA1 (1.00) | CA1CA2CA4CA12CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106960-A | Fiber-reactive and monoazo red and yellow dyes; color- and washfastness; formaldehyde-resistance; brightness | CIBA-GEIGY CORPORATION (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0039306-A1 | Azo dyestuffs, methods for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-11-04 | — | — | EP | disclosed |