Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10514927 | 0.72 | RAB9A (0.46) | RAB9ANPSR1NPC1KAT2AKAT2B | |
| SCHEMBL9644558 | 0.68 | ALOX5 (0.38) | RAB9ANPC1CRBNKMT2AMEN1 | |
| SCHEMBL9645242 | 0.68 | CRBN (0.52) | RAB9ANPSR1NPC1CRBNPOLB | |
| SCHEMBL28207007 | 0.67 | RAB9A (0.56) | RAB9ANPSR1NPC1KAT2AKAT2B | |
| SCHEMBL7745143 | 0.67 | CRBN (0.52) | RAB9ANPSR1NPC1KAT2AKAT2B | |
| SCHEMBL9184204 | 0.65 | NPC1 (0.54) | RAB9ANPSR1NPC1KAT2AKAT2B | |
| SCHEMBL9465324 | 0.64 | RAB9A (0.53) | RAB9ANPSR1NPC1KAT2AKAT2B | |
| SCHEMBL8310458 | 0.64 | KDM4E (0.48) | RAB9ANPSR1NPC1KAT2AKAT2B | |
| SCHEMBL21047628 | 0.64 | RAB9A (0.65) | RAB9ANPSR1NPC1CRBNKMT2A | |
| SCHEMBL21480878 | 0.64 | NPC1 (0.52) | RAB9ANPSR1NPC1KAT2AKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5086052-A | Antiarthritic, antiallergens, antiinflammatory agents; also for asthma and psoriasis | ABBOTT LABORATORIES (US) | 1992-02-04 | — | — | US | disclosed |
| US-4970210-A | ENZYME INHIBITORS | ABBOTT LABORATORIES (US) | 1990-11-13 | — | — | US | disclosed |